10 of the Worst Pandemics in History

Worst Pandemics

The year 2020 is one of the pandemic years we have come across. You would be surprised to know that this year marks the 100th anniversary of the deadliest event in the world’s history till date.

Whenever our human species deals with such pandemic activity, we all are heartbroken and our world decreases to a level we cannot even imagine. But in the last 100 years, we have progressed ourselves and tried our level best in experimenting with medical science and research to find medication for such pandemic diseases.

Now, let’s have a look at the world’s worst pandemics in the last 100 years and how we dealt with it.


Influenza Flu

The starting flu period came with the largest death toll all over the globe. The world’s one-third population was affected due to this and ended the lives of 20-50 million people. Many people also refer to this flu as ‘Spanish flu’ because this flu was first observed in Europe and then it was swiftly spread across the world.

Influenza or flu was highly contagious. It directly attacks the respiratory system and it is an infectious disease that can be spread directly from one person to another. At that time, we did not have any drugs or vaccines to threaten the flu strain.

All the citizens of the country were requested to wear masks.

Many countries advised their citizens to shut down their business and schools, colleges, etc were also shut down.

But after all these precautions, we lost almost one-third of our population.



Tuberculosis is an infectious disease. Mycobacterium Tuberculosis bacteria is the cause of this disease. It is found in every country of this globe and around 1.8 billion people are infected with this illness. It is responsible for the death of millions. According to the figures, 10 million people were affected due to this last year and 1.5 million lost their lives. Reports provided by WHO shows that 4109 people die on a daily basis from this illness around the world. It was first found in Egypt and other countries. Since it is a very old disease, medical professionals have now made a vaccine for this disease and it can be cured nowadays.

3. SARS (2002-2003)

SARS (2002-2003)

Acute respiratory syndrome is a viral disease caused by Coronavirus. It is also related to Coronavirus as both the viruses came from the same family (SARS-CoV). The first patient reported was in Asia in 2002. Lately, it got spread to different parts of the world including North America, South America, Europe and many more. According to WHO reports, 8,098 people got infected due to this and 774 even lost their lives. The medical professionals were unable to find an antidote for this. This is an infectious disease and spreads so quickly by person-to-person contact.


H1NI Influenza Flu

The 2009 flu is also known as (H1N1) pdm09 virus. The virus contained a new influenza gene that was not previously found in any living species either it is an animal or a human being. It was first discovered in the United States and spread across the world within a short span of time.

It was found out that it had affected 60.8 million people across the globe in a time span of April 12, 2009- April 10, 2010. The number of hospitalized patients was 274,304 and 12,469 lost their lives. In order to decrease the mortality rate, medical professionals and researchers invented a vaccine named monovalent (H1N1) pdm09 vaccine but it was not available in large quantities till late November due to which we lost half of our population.



Ebola is an acute and infectious disease which was first recorded (on a wide scale) in Guinea, December 2013. Later on, the disease spread on to Liberia and Sierra Leone. It comes under the family of Pteropodidae. It’s spread from human-human contact.

According to the reports provided by WHO a total of 28,646 got infected due to this at that time and 11,323 were dead. It mainly affected senior citizens and toddlers and people having a weaker immunity. After spending a lot of time WHO finally comes up with some of the tests that determines whether a person is Ebola positive or negative like NAT for routine diagnostic management and rapid antigen detection test. A vaccine, called rVSV-ZEBOV got prepared for its prevention but was not able to get clinical approval. There is no Ebola specific treatment that presently exists but one can take some measures to prevent it.

6. HIV/AIDS (ongoing)

HIV/AIDS (ongoing)

Human immunodeficiency virus is also known as HIV which causes Acquired Immunodeficiency Syndrome which is a life-threatening disease. It was first reported in 1981 and since that time till now more than 25 million people have died from this disease and approximately 37.9 million people are infected and living with this disease around the globe. The mortality peak increased in 1997 when the number reached 3.3 million per year. The most affected region from this disease is Sub-Sahara Region. Almost 61% population was infected from HIV/AIDS in this region. It is a transmittable disease and its spread through human-human interaction. With such medical advancements in today’s world, we are still not able to invent the vaccine or antidote for it. Only precautions are effective in this disease.



Coronavirus (COVID-19) is an ongoing pandemic illness that our generation is suffering from.  Wuhan, Hubei China recorded the first case of coronavirus in December 2019. WHO declared this illness pandemic on 11th March 2020? 575,444 people are suffering from this illness and 26,654 people have lost their lives. It is transmitted from human-human interaction. Most of the countries have announced a lockdown in their area and there is no public transportation all over Asia. People suffering from this illness are mostly senior citizens and people having a weaker immunity. Scientists and medical professionals have created kits for testing the disease but there are no vaccines or Antidote present till now.


These are the list of some of the worst Pandemics which occurred in the last 100 years. These Pandemic diseases caused lots of deaths in different countries and made a great impact of fear on the minds of people. It also took so many days to generate vaccines for Pandemic diseases. Among them, some of the disease vaccines are still not available in different hospitals to fight with deadly viruses.

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